A Study Breakdown

Cannabis 

Amyotrophic Lateral Sclerosis (ALS)

• Study 1: Amyotrophic Lateral Sclerosis: Delayed Disease Progression in Mice by Treatment with a Cannabinoid. (Raman, Chandrasekaran, et al., 2004) — Explores cannabinoids’ role in delaying ALS progression.
• Study 2: Emerging Potential of Cannabidiol in Reversing Proteinopathies. (Dash, Raju, et al., 2021) — Highlights CBD’s potential in addressing protein misfolding diseases.
• Study 3: Effectiveness of Medical Cannabis for Psychiatric, Movement, and Neurodegenerative Disorders. (Lim, Keane, et al., 2017) — Systematic review covering multiple disorders.

Arthritis

• Study: Cannabis Use Assessment and Its Impact on Pain in Rheumatologic Diseases. (Guillouard, M, et al., 2020) — Systematic review showing reduced pain in arthritis patients.

Antimicrobial/Bacterial Properties

• Study: The Antimicrobial Activity of Cannabinoids. (Karas, John A., et al., 2020) — Evaluates the antimicrobial potential of cannabinoids.

Antioxidant Properties

• Study: CBG, CBD, ∆9-THC, CBN, CBGA, CBDA, and ∆9-THCA as Antioxidant Agents. (2021) — Explores the antioxidant potential of multiple cannabinoids.

Bladder Disorders

• Key Studies:
  • Endocannabinoids in Bladder Sensory Mechanisms. (Christie, Stewart, et al., 2021)
  • Functional Role of Cannabinoid Receptors in Urinary Bladder. (Tyagi, Pradeep, et al., 2010)

Bone Health

• Studies:
  • Cannabinoids in Bone Fracture and Joint Disease Prevention. (Palmini, Gaia, et al., 2022)
  • Role of Cannabinoids in Bone Remodeling. (Idris, Aymen I., et al., 2012)

Crohn’s Disease

• Studies:
  • Cannabis Treatment for Crohn’s Disease: Observational Study. (Naftali, Timna, et al., 2011)
  • Cannabis Induces Clinical Response in Crohn’s Patients. (Naftali, Timna, et al., 2013)

Cancer

Cannabis and its cannabinoids have shown promising potential in cancer treatment and supportive care:

• Study 1: The Interplay between Cancer Biology and the Endocannabinoid System (Moreno, Estefanía, et al., 2020) highlights the role of the endocannabinoid system in influencing cancer risk, prognosis, and treatment outcomes.
• Study 2: Synergistic Cytotoxic Activity of Cannabinoids from Cannabis Sativa against CTCL (Mazuz, Moran, et al., 2020) emphasizes the combined effects of CBD and THC in treating cutaneous T-cell lymphoma.
• Study 3: Cannabinoids as Anti-Cancer Agents (Ladin, D. A., et al., 2016) presents preclinical and clinical insights into cannabinoids’ effectiveness as anti-cancer agents.
• Study 4: Enhanced Anticancer Effects with Phytocannabinoids and Chemotherapy (Scott, Katherine A., et al., 2017) investigates how the sequence of cannabinoid administration can improve efficacy.
• Study 5: Opportunities for Cannabis in Supportive Cancer Care (Kleckner, Amber S., et al., 2019) explores cannabis’ potential in managing symptoms and improving the quality of life for cancer patients.

Fibromyalgia

Research reveals significant benefits of cannabis in managing fibromyalgia symptoms:

• Study 1: Medical Cannabis for Fibromyalgia Safety and Efficacy (Sagy, Iftach, et al., 2019) demonstrates reduced pain and improved quality of life.
• Study 2: Characteristics of Cannabis Use in Fibromyalgia Patients (Habib G, Levinger U, 2020) provides insights into patient experiences.
• Study 3: THC-Rich Cannabis Oil in Fibromyalgia (Chaves, Carolina, et al., 2020) highlights positive outcomes in a controlled clinical trial.
• Study 4: Retrospective Open-Label Series on Fibromyalgia (Mazza, Manuela, 2021) discusses cannabis’ role in fibromyalgia syndrome treatment.

Gastrointestinal Health

Cannabinoids play a pivotal role in maintaining and protecting gastrointestinal health:

• Study: Cannabinoids in Gastrointestinal Defense and Inflammation (Gyires, Klára, et al., 2016) reviews the effects of cannabinoids on inflammation, mucosal protection, and gastrointestinal disorders.

Inflammation

Research highlights the anti-inflammatory properties of cannabis compounds:

• Study 1: Medical Cannabis Compounds and Anti-Inflammatory Modes of Action (Anil, S. M., et al., 2022) identifies THC, CBD, and CBG as significant contributors.
• Study 2: Endocannabinoid System’s Role in Inflammation and Neurogenesis (2021) summarizes findings from animal models.
• Study 3: Bioactive Cannabis Compounds Against Oxidative Stress and Inflammation (Kopustinskiene, Dalia M., et al., 2022) emphasizes the protective roles of cannabinoids.

Cannabidiol (CBD)

• Anti-Anxiety: Potential of CBD for Anxiety Disorders. (Blessing, Esther M., et al., 2015)
• Pain: CBD’s Effectiveness in Pain Management. (Boehnke, Kevin F., et al., 2016)
• Neuroprotection: CBD’s Role in Alzheimer’s Disease Prevention. (Currais, Antonio, et al., 2016)

Cannabichromene (CBC)

• Anti-Inflammatory: CBC’s Role in Inflammation Reduction. (Ghasemi Gojani, et al., 2023)
• Pain Management: Antinociceptive Effects of CBC. (Maione, Sabatino, et al., 2011)

Cannabigerol (CBG)

• Neuroprotection: CBG’s Efficacy in Huntington’s Disease. (Valdeolivas, Sara, et al., 2014)
• Anti-Inflammatory: CBG in Rheumatoid Arthritis. (Lowin, Torsten, et al., 2023)

Cannabinol (CBN)

• Sleep Improvement: CBN and Sleep Quality. (Bonn-Miller, Marcel O., et al., 2023)
• Neuroprotection: CBN for Oxytosis Prevention. (Liang, Zhibin, et al., 2022)